Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity connected with bortezomib, a proteasome inhibitor Utilized in the procedure of several myeloma. Its synthesis or research is essential for guaranteeing the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the cure of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound within the synthesis of imatinib, a drug that targets specific different types of most cancers, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers including breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates inside the synthesis of gemcitabine, an anti-cancer drug. Their review is important for optimizing the production approach and ensuring superior purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is applied to take care of breast most cancers, and these intermediates are involved with its creation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the CAS NO. 136572-09-3 treatment method of breast most cancers. A variety of intermediates help in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers including ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the therapy of colorectal most cancers and tiny cell lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved with the synthesis of adamantane derivatives, that have various apps, which include antiviral Houses.
Vildagliptin Intermediates: Utilized in the production of vildagliptin, an oral drug for variety two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of varied gluconic acid derivatives, which happen to be Employed in food stuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor from the CAS NO. 1016636-76-2 synthesis of canagliflozin, a medication applied to control variety 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).